For the first time since Week 1, the San Francisco 49ers finally have all their key offensive weapons available.

The San Francisco 49ers made a significant roster move that doesn't bode well for one of their top defensive players.

Call Sunday’s Niners-Cardinals showdown the Battle of Wounded Knee… and Leg, and Shoulder, and Feet, and even Appendixes. You ...

Ahead of their game against the Cardinals, the 49ers got a bunch of great health news, though they did add one player to the ...

San Francisco and Arizona are in separate stages of quarterback drama as they prepare to conclude their season series Sunday ...

The San Francisco 49ers' defense took a new hit with the news that corner Deommodore Lenoir suffered an injury in Thursday's ...

It feels like it has been a lifetime since the Arizona Cardinals last squared off with the San Francisco 49ers, but that was ...

The 49ers have the worst pass rush in the NFL by many measures, but Robert Saleh is hopeful they will improve.

The Seahawks and Rams have a pair of the league's most explosive playmakers, but here's why Sunday's game might be determined ...

Matt Maiocco highlights five key 49ers to keep an eye on in San Francisco's pivotal Week 11 matchup against the Arizona Cardinals on Sunday.

San Francisco 49ers offensive lineman Dominick Puni joined "You've Got Mail" presented by Delta Dental to discuss his Midwest upbringing, family of athletes, college journey, locker room traditions, ...

The Los Angeles Rams, led by 17th-year quarterback Matthew Stafford, have been absolutely dominant as of late. They have now ...