Persistence of SF3B1 with loss of JAK2 and CBL suggests clonal sweeping during leukemic transformation. These results highlight the need for vigilance in long-term follow-up of ostensibly low-risk MDS ...

Benefit with luspatercept persisted in SF3B1-mutated and wild-type disease and at higher variant allele frequencies. Luspatercept demonstrated superior red blood cell transfusion independence and ...

A defective gene normally found in blood cancers could be treated with drugs already available for cancers with similar gene defects, scientists at the University of Birmingham and Queen’s University ...