Current lentiviral vector systems (the third generation ... systemic delivery of these vectors remains a major hurdle that has stymied gene therapy applications. But there’s movement.

"Our results suggest that patients who are considering lentiviral vector gene therapy should continue to be educated on the ...

Gene therapy for SCID-X1 ... leukemogenesis with further genetic abnormalities. gretroviral and lentiviral vectors with a vector-specific nonrandom integration pattern in target cell genomes ...

The popularity of viral vector-based gene therapies and vaccines is rapidly growing ... note from Thermo Fisher Scientific to learn how scientists have used their lentiviral production system, ...

RP-L102, which the firm designed to treat a form of disease caused by FANCA mutations, is already under review with the European Medicines Agency.

Known as Zynteglo in Europe where it is approved to treat the rare blood disorder beta-thalassemia, the gene therapy has been ... very unlikely our BB305 lentiviral vector played a role in this ...

Another gene therapy produced by bluebird bio is Zynteglo (betibeglogene autotemcel or beti-cel), a lentiviral vector gene ...

Gene-202, and to further develop its proprietary lentiviral vectors. The vectors are designed to be applicable to a range of liver-related metabolic disorders and, as its first indication, the company ...

Prof. Dr. Janine Reichenbach, co-founder of Somagenetix, said: “To date, my team at the University of Zurich has developed a best-in-class lentiviral gene therapy platform for phagocytes ...

RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt their lineage commitment during gene therapy based on the underlying genetic ...

Its multi-platform development approach applies the lentiviral vector and adeno-associated viral vector gene therapy platforms. Its clinical program is an LVV-based gene therapy for the treatment ...

Gene therapy for SCID-X1 ... leukemogenesis with further genetic abnormalities. gretroviral and lentiviral vectors with a vector-specific nonrandom integration pattern in target cell genomes ...