Thoracic aortic aneurysm (TAA) is a significant public health concern. We aimed to identify drug targets and understand the pathogenic mechanisms of TAA. We employed 4907 circulating proteins as ...
This study presents a useful compendium of triangulated single-cell eQTLs, Mendelian randomisation and colocalization of genetic signals in prostate cancer datasets. Biological interpretation in the ...
CellColoc is a Python package for interactive, segmentation-based colocalization analysis in microscopy images. It is designed for experiments where you want to: segment a larger biological object in ...
We utilized the largest available genome-wide association study (GWAS) datasets for European individuals, including summary data for AF (N = 1,030,836) and BC (N = 247,173). Multiple approaches were ...
The Sikkim flood of October 2023: Drivers, causes, and impacts of a multihazard cascade Planar cell polarity (PCP) is an essential property of tissues in which subcellular protrusions or polarized ...
The proteome is a key source of therapeutic targets. We conducted a comprehensive Mendelian randomization analysis across the proteome to identify potential protein markers and therapeutic targets for ...
Kidney stone disease (KSD) is facing rising global prevalence and recurrence rates. Mendelian randomization aids in drug repurposing and the discovery of therapeutic targets. This study utilized ...
Abstract: Automatic analysis of colocalizing biological structures in multi-channel fluorescence microscopy images is an important task to quantify and understand biological processes at high ...
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