The Israel Defense Forces said the air force had launched strikes against missile sites in central Iran, as the Middle East conflict entered a fourth day.

World leaders had gathered Monday in Canada with the specific goal of helping to defuse a series of global pressure points, only to be disrupted by a showdown over Iran’s nuclear program that could escalate in dangerous and uncontrollable ways.

After canceling negotiations with the U.S. scheduled for Sunday, Tehran has signaled it is willing to talk.

Gold pushed higher in early Asia trading after US President Donald Trump called for the immediate evacuation of Tehran, boosting demand for havens as investors track hostilities between Israel and Iran.

White House press secretary Karoline Leavitt cited the Israel-Iran conflict in announcing Trump's plans to depart the Group of Seven summit in Canada a day early.

Iranian officials have warned that U.S. participation in an attack on its facilities will imperil any chance of the nuclear disarmament deal the president insists he is still interested in pursuing.

US President Donald Trump is reportedly expected to offer Iran a 'last chance' nuclear offer which may be slightly better than the previous proposal just over a week ago