Cystic fibrosis is caused by mutations in the gene that produces the cystic fibrosis transmembrane conductance regulator (CFTR) protein. In people with CF, mutations in the CFTR gene can disrupt the ...

There are five classes of CFTR mutations: protein production, protein processing, gating, conduction, and insufficient protein. The most common CF mutation, F508del, is primarily considered to be a ...

I spent my childhood and young adulthood being told I was “too young and healthy” to be dealing with the health issues I experienced. But as an adult, I was determined to find answers, and eventually, ...

Growing up with CF, running was never an easy thing for me. Despite that, I dedicated myself to my school’s cross-country team for years and earned a spot on the varsity team. When the chance to ...

The looming awareness of my own mortality from cystic fibrosis fueled years of substance misuse. But after hitting bottom and seeking help through a health program, I have been sober since August 2024 ...

I was diagnosed with cystic fibrosis as a baby, only to be told later that I didn't have it. As an adult, I began to face persistent health challenges and had to become my own advocate, pushing for ...

Help make CF stand for Cure Found. Give Once Give to a Walker Other Ways to Give ...

Despite its prevalence and impact, there is no CF-specific guidance for the assessment and management of pain. The Cystic Fibrosis Foundation assembled an expert panel of clinicians, researchers, ...