A human heart might contract some three billion times over a lifetime, and each one of those contractions is driven by a protein called myosin. One of three classes of so-called motor proteins in our ...

We combined protein engineering and single molecule measurements to directly record the step size of a series of myosin constructs with shortened and elongated artificial neck domains. Our results ...

Contractile proteins are proteins that mediate sliding of contractile fibres (contraction) of a cell’s cytoskeleton, and of cardiac and skeletal muscle. Heart and muscle contractile fibres consist of ...