Pope Francis suffered two episodes of acute respiratory failure Monday, the Vatican said, a fresh setback in the worst health crisis of his papacy.

Pope Francis on Monday suffered two attacks of "acute respiratory insufficiency," the Vatican said, as the 88-year-old continues his health fight.

Pope Francis, 88, has been in a critical condition due to a lung infection. His two weeks in Rome's Gemelli hospital is the longest stay of his papacy and underscores his frailty. Francis has made more than 45 international trips during his papacy,