Multiple long-term conditions (MLTC, previously referred to as multimorbidity) are defined as two or more chronic health ...

Paediatric sepsis remains a major cause of childhood mortality worldwide, despite substantial changes in its epidemiology, ...

Functional neurological disorder is a common reason for children to present to the emergency department, but education gaps contribute to delays in diagnosis. This can result in unnecessary diagnostic ...

Background The widespread use of pneumococcal conjugate vaccines (PCV) has changed the epidemiology of invasive pneumococcal disease (IPD) in children globally. Methods Multicentre prospective audit ...

Objective To establish the relative risks of in utero exposure to lamotrigine (LTG), sodium valproate (NaV) and carbamazepine (CBZ) monotherapy for neurodevelopment. Design Observational cohort study.

Correspondence to Dr John Murphy, Department of Neonatology, The National Maternity Hospital, Holles Street, Dublin 2, Ireland; johnmurphy104{at}hotmail.com Aims Currently there is debate on how best ...

Correspondence to Marije A Brouwer, Department of Pediatrics, University Medical Center Groningen, Groningen 9700 VB, Netherlands; m.a.brouwer{at}umcg.nl Objective Breaking bad news about ...

Objective When infants suffer from nasal congestion, xylometazoline spray or drops can be effective to facilitate breathing and drinking. However, case reports on side effects have resulted in ...

Correspondence to Dr Defne Saatci, Population Policy Practice, Institute of Child Health, London WC1N 1EH, UK; defne.saatci.16{at}ucl.ac.uk Objective To assess differences across educational outcomes ...

Introduction Fluid overload of 10% at 48 hrs (100 ml/kg additional fluid) is strongly associated with morbidity in critically ill children.1 Contributors include fluid resuscitation, acute kidney ...

aDepartments of Medicine (Division of Endocrinology and Metabolism) and Biochemistry and Molecular Biology, University of Florida, College of Medicine, Gainesville, Florida, bDepartment of Medicine ...

In 2025, a government-commissioned, independent, cross-sector report on the decline in UK clinical academia highlighted multiple challenges facing clinical researchers, both those medically qualified ...