Prion infections lead to invariably fatal diseases of the CNS, including Creutzfeldt–Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE), and scrapie in sheep. There have been ...

Wildlife officials in the U.S. and Canada report cases of chronic wasting diseases where it hasn't been detected before.

Scientists have detected abnormal prion protein in the skin of several people who died from Creutzfeldt-Jakob disease (CJD). The scientists also exposed healthy mice to skin extracts from two CJD ...

Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein ...

The misfolding of proteins and their subsequent deposition as amyloid in peripheral nerves lead to sensory and autonomic neuropathy A new hereditary form of neuropathy, prion protein (PrP) systemic ...

Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. Case Western ...

We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease. Called prions, these molecules are responsible for conditions such as bovine ...

Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...

Prion diseases are progressive nervous system diseases which always have a fatal outcome. They are transmissible and affect many mammals. They are also called transmissible spongiform encephalopathies ...

The virus causing the ongoing COVID-19 pandemic, SARS-CoV-2, has spread far more quickly than any other coronavirus in recorded history. Why is it so contagious? One possibility is that its spike ...