The NFL's upcoming lineup of games is rife with questions. But there's little question that the Chiefs are approaching must-win territory in Week 12.

On the other side, Davis Mills (filling in again for the injured C.J. Stroud) won't face as difficult a unit in the Bills defense. Sean McDermott's defense has given up at least 30 points in back-to-back games and has one of the worst run defenses in the NFL, allowing teams to average 153 yards per game on the ground (31st).

Week 12 of the NFL season is here, and it's already shaping up to be another prime week for fantasy managers. From breakout stars to disappointing dud performances, making the right start or sit calls can make or break your lineup,

The Los Angeles Rams and Tampa Bay Buccaneers will duke it out in a highly anticipated matchup between star quarterbacks in Week 12 of the NFL season.

Sportsbooks expect this to be both a blowout and a low-scoring affair in Tennessee on Sunday when the Seahawks visit the Titans. Seattle has one of the league's best defenses while Tennessee has the NFL's worst offense under rookie quarterback Cam Ward. There are only two games with totals lower than this one at BetMGM as of Thursday.

Entering Week 11, Buffalo’s odds of making the playoffs jumped back up to 90% (was 86%); their odds of winning the division dropped to 28% (was 29%). As for earning a playoff bye, the Bills’ odds improved to 10% (was 9%), while Buffalo’s odds of making it to the Super Bowl saw a similar improvement to 14% (was 13%).

Mike Florio and Chris Simms look ahead to a stinker of an NFC South rivalry game between the Falcons and Saints with nothing but pride on the line amid QB questions for both squads.