Protective borders between the brain and the blood weaken with age. This includes the barrier formed by tightly linked epithelial cells in the choroid plexus, which generates cerebrospinal fluid. In ...

Researchers identify tanycytes as a critical mechanism for clearing toxic tau protein from the brain, offering a new target ...

A grape-like structure in the brain called the choroid plexus becomes enlarged and shows increased accumulation of abnormal inflammatory molecular signaling in people with Alzheimer's disease, ...

The image of the “blood-brain barrier” as a static wall that shields the brain from the rest of the body is crumbling. A group of scientists argue, in a review published in Fluids and Barriers of the ...

Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...

Enough pints of beer can have you falling off your bar stool or loudly reciting lyrics to early 2000s jams to total strangers, because alcohol can get past one of the strongest defenses in the body.

A test measuring proteins in spinal fluid may help support the diagnosis of MS, especially in patients whose disease is harder to diagnose.

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...

A novel blood and cerebrospinal fluid (CSF) measure showed promise as a biomarker for Parkinsonian disorders. CSF levels of DOPA decarboxylase (DDC) -- an enzyme that converts levodopa into dopamine - ...

The blood-brain barrier plays an essential role in protecting the central nervous system from harmful bacteria, toxins, and other blood-borne pathogens. The blood-brain barrier plays an essential role ...