Adrenal gland cancer, computer illustration. The authors explore the etiology and clinical presentation of primary and secondary aldosteronism as well as medical and surgical treatment options.

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Please provide your email address to receive an email when new articles are posted on . Primary aldosteronism, an adrenal disorder and a secondary cause of hypertension, has historically been ...

For permission requests, please contact NEJM Reprints at [email protected] We have recently observed a patient with malignant hypertension and hyperaldosteronism who also had an impairment in renal ...

“Although guidelines recommend testing for primary aldosteronism in all patients with treatment-resistant hypertension, we found very low rates of screening for primary aldosteronism — on average 2% ...

Other recent outcome studies document that resistant hypertension is not rare. In the Controlled ONset Verapamil INvestigation of Cardiovascular End Points trial (CONVINCE), [2] more than 16,600 ...

Dr. Aaronson answers the question: 'Aldosterone Antagonist Side Effects?' — -- Question: What are the benefits and side effects of an aldosterone antagonist? Answer: Thanks to research led by Dr.

The clinical presentation of hyperaldosteronism varies by case and ranges from asymptomatic to mild to severe symptoms including hypertension, hypokalemia, nausea, fatigue, headache, edema, ...