Thymus is the key organ for development and maturation of T lymphocytes. The dysfunction of thymus leads to decreased immunity or autoimmune diseases. T cells can be divided intoαβ T cells and γδ T ...

An international research team led by scientists at the City of Hope reports that they have demonstrated a way in preclinical studies to boost thymic function after damage in preclinical studies. The ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical ...

In recent years, the field of immunology has increasingly focused on the role of glycolipids and sphingolipids in the differentiation and function of innate immune cells, such as macrophages, ...

Vijay K. Kuchroo, PhD, DVM, of the Gene Lay Institute of Immunology and Inflammationof Brigham and Women’s Hospital, Massachusetts General Hospital and Harvard Medical School and the Ann Romney Center ...