Iowa State basketball star Joshua Jefferson left Friday's NCAA Tournament game with a left-ankle injury and will not return for the remainder of the game.

With or without Joshua Jefferson, Iowa State will have its hands full against a talented Kentucky squad in the second round.

GREENVILLE, S.C. – March Madness has officially arrived! The eighth-seeded Ohio State Buckeyes square off against the ninth-seeded TCU Horned Frogs in the East Region today, Thursday, March 19. There are multiple streaming options to watch this game.

Iowa State forward Joshua Jefferson is unlikely to play against Kentucky in the second round of the NCAA men's tournament, coach T.J. Otzelberger said Saturday.

Markhi Strickland (11.8) and Treyson Anderson (10.4) are also factors offensively. Carson and Anderson lead with 6.4 and 5.4 rebounds per game. Andy Stefonowicz ties those four together with 4.9 assists per game.