A research team, led by Professor Ja Yil Lee in the Department of Biological Sciences at UNIST has made a breakthrough in the field of molecular biology. Their research, published in the journal ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

A team of researchers at the University Medical Center Schleswig-Holstein (UKSH), Kiel Campus, the Kiel University, and the Max Planck Institute for Molecular Genetics, Berlin, have developed an ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...

Single-stranded DNA-binding proteins (SSBs) protect transiently exposed ssDNA, yet how DNA polymerase (DNAp) displaces them during replication remains unclear. Using single-molecule force spectroscopy ...

Multiomic Characterization of RCC1 and RCC2 Expression and Their Association With Molecular Alterations, Immune Phenotypes, and Cancer Outcomes This retrospective analysis included patients with ...

Microsimulation comparing three mt-sDNA rounds versus one colonoscopy over 10 years incorporated real-world adherence, test performance, and natural history to estimate lesion detection, CRC incidence ...

Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help ...