Researchers in the Blavatnik Institute at Harvard Medical School have opened a new window into understanding the development of antibiotic resistance in bacteria. The work not only reveals principles ...

Plasmids –autonomously replicating DNA molecules– exhibit a broad range of replication and mobility strategies, genetic repertoires, host ranges, sizes, and copies per cell. However, the determinants ...

To examine which genetic elements are involved in the generation of resistance islands, we identified all the gene families encoding either transposases or site-specific recombinases (collectively ...

Scientists have identified essential genetic code for a method called plasmid curing, which aims to 'displace' antibiotic resistance genes from bacteria. Birmingham scientists have identified ...

Addgene, a purpose-driven organization helping scientists conduct experiments with greater ease, speed, and reproducibility, today announced a strategic partnership with Promega to expand Addgene’s ...

The term “plasmid” was coined by Joshua Lederberg in 1952 to describe extrachromosomal genetic elements observed during studies of bacterial conjugation and antibiotic resistance. Their transformation ...

A Dartmouth study finds that molecular hitchhikers living within bacteria can make their hosts extra resistant to medical treatment by corralling them into tightly packed groups. The findings ...