Get the opening NFL Week 10 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Nov. 6, 2025.

Just how dominant were favorites in the first month of the NFL season? They won 73% of the games (46-17-1 SU) and covered the point spread at a 56.3% clip (36-28 ATS). Suffice to say, the script flipped in Week 5, when underdogs barked in a very big ...

Who will win on Monday Night Football in NFL Week 6? The Arizona Republic is predicting a 31-30 win for the Commanders over the Bears in the NFL Week 6 Monday Night Football game. Jeremy Cluff writes: "The Commanders overcame a 10-0 deficit in their win ...