Texans (+5.5) over Bills. Buffalo's defense is reeling at the moment, allowing 30 or more points in back-to-back games. The Bills' run defense has been abysmal, surrendering 5.4 yards per carry (second most in the NFL). That could result in a strong day for the Texans on the ground, which could help tip the scales in favor of an upset.

The MVP quarterback was battered and harassed, as he was sacked a career-high eight times in this Thursday Night Football game. The Texans, whose defense entered Week 12 ranked first in the NFL in total yards, handled Allen and his line, causing him to throw two interceptions and post a 67.4 passer rating.

The other quarterback is coming off a historic game. Reigning NFL MVP Josh Allen had six touchdowns last week, three passing and three receiving. Allen now has two of three games in NFL history with three passing touchdowns and three rushing touchdowns. Otto Graham has the other, in 1954.

We'll also take a look ahead to college basketball's "Feast Week" and, of course, break down the high-stakes matchups in the NFL and college football this weekend. Let's dive in. The Texans upset the Bills in a "Thursday Night Football" thriller.

The Buffalo Bills' MVP is one rushing TD away from becoming the NFL's all-time leader in rushing TDs by a QB. Will he get it Thursday?

The Buffalo quarterback made a new friend with the Amazon Prime Video NFL analyst’s beloved pet before facing the Texans.

For the 17th time in his NFL career, Buffalo Bills quarterback Josh Allen has once again been named AFC Offensive Player of the Week (OPotW). The latest award follows a dominant performance against the Tampa Bay Buccaneers, though his efforts were several steps closer to legendary.

Josh Allen and his Buffalo Bills teammate Gabe Davis suffered a hilarious blunder on the sidelines on Sunday, Nov. 16 when their helmets got stuck together after a headbutt gone wrong.