Mitochondria fuel your muscles, immune system and cellular repair – and their performance affects everything from fitness to ...

Mitochondrial DNA (mtDNA) mutations impair OXPHOS and enhance lactate accumulation in skeletal muscle. Elevated lactate drives H3K14 histone lactylation, inducing GDF15 expression and secretion in ...

Scientists have discovered that boosting the COX7RP protein enhances cellular energy efficiency and significantly extends ...

Duchenne muscular dystrophy (DMD) causes dysfunction of muscle cells that help move blood through the circulatory system, a ...

A new study reveals that vesicles packed with healthy mitochondria can supercharge tissue repair and combat chronic disease, paving the way for next-generation regenerative treatments. Study: ...

We all learned in high school biology that mitochondria are the powerhouse of the cell. But powering up those cellular engines requires a molecular spark. Now, scientists at the Salk Institute have ...

MA-5 is a therapeutic intervention for mitochondrial disease that has been demonstrated to ameliorate severe symptoms such as neurological disorders, renal dysfunction, hepatic dysfunction and motor ...

When I tried statin therapy as part of an experiment, I quickly developed a common side effect. But what concerned me wasn’t ...

Grants include research funding in amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease (CMT), Duchenne muscular dystrophy, facioscapulohumeral muscular dystrophy (FSHD), mitochondrial ...

High-intensity interval training outperforms standard home exercise in improving fitness for patients with inflammatory ...