Please provide your email address to receive an email when new articles are posted on . Epinephrine with a local anesthetic is safe and effective with no instances of digital necrosis or need for ...

Postoperative pain is common after most surgical procedures, including laparoscopic colorectal surgery 1. Currently, multimodal analgesic methods such as preperitoneal infusion, epidural analgesia, ...

Tendon surgery in the pediatric lower extremities could cause severe postoperative pain, leading to psychological distress and chronic pain. Local wound anesthesia could significantly improve ...

Liposomal bupivacaine was launched on the market 12 years ago to provide long-lasting local control of pain. The medication is used as a local anesthetic, particularly for orthopedic operations. A ...

Preventing metastases by using perioperative interventions has not been adequately explored. Local anesthesia blocks voltage-gated sodium channels and thereby prevents activation of prometastatic ...

Peritumoral injection of a local anesthetic before breast cancer surgery significantly increased disease-free survival (DFS) and overall survival (OS) in women with early breast cancer, a randomized ...

Minimizing the use of sedatives during operations could shorten hospital stays and reduce the risk of complications. Immersing patients in virtual reality could help reduce the amount of local ...

A simple observation of numbness from coca leaves led to a medical revolution. Scientists isolated cocaine, revealing its ...

Long-Term Outcomes and Molecular Correlates of Sotorasib Efficacy in Patients With Pretreated KRAS G12C-Mutated Non–Small-Cell Lung Cancer: 2-Year Analysis of CodeBreaK 100 Preventing metastases by ...