Precursor mRNA splicing to remove introns and join exons, producing mature mRNA, is a key regulatory step for gene expression. Canonical pre-mRNA splicing of introns is catalysed by a large complex of ...

Most mammalian genes undergo alternative splicing. The splicing of some exons has been acquired or lost in specific mammalian lineages, but differences in splicing within the human population are ...

Feasibility of consensus molecular subtype classification of colorectal cancer using preoperative biopsy specimens: A prospective pilot study.

While working on a COVID-19-related project during the lockdown, Kärt Tomberg, PhD, found herself thinking about introns. She was part of a team working on the spike protein used in vaccines. Her task ...