Surprised researchers discover hormone-sensitive lipase in the nuclei of fat cells, part of a finely tuned system that ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

Uncovering the mystery of why individuals born with mutations in the gene that encodes HSL—the cytosolic enzyme that releases energy from fat—lose fat instead of gaining it, Dominique Langin, PhD, ...