Peptides have long attracted attention in the scientific community due to their structural simplicity yet vast range of ...

A link between energy balance and reproduction is critical for the survival of all species. Energy-consuming reproductive processes need to be aborted in the face of a negative energy balance, yet ...

Astrocytes in the hypothalamus release prostaglandin E₂ (PGE₂) in response to cell-cell signaling initiated by neurons and glial cells. Upon release, PGE₂ stimulates the secretion of ...

One in 800 children are born with Down syndrome, the most common genetic cause of intellectual disability. The vast majority of cases are caused by having three copies of chromosome 21 instead of two.

Men with hypogonadotropic hypogonadism caused by congenital combined pituitary hormone deficiency may see an increase in serum testosterone levels with the use of gonadotropin-releasing hormone ...

Patients with Down syndrome face a lifetime of sensory, reproductive and intellectual disabilities that worsen with age. But despite affecting as many as 1 in 700 births, according to the Centers for ...

Data from the PREFER study—a large, multicenter prospective cohort in Italy—show that while most premenopausal women with early breast cancer opted for GnRHa therapy to protect their ovaries during ...