Nucleic acid (NA) based tests are increasingly being used across various disease conditions for diagnosis, prognosis, for treatment decisioning and can be scaled up very quickly in both central lab ...
RBPs dynamically interact with their RNA targets to regulate RNA fate in all aspects, including transcription, splicing, modification, localization, translation and degradation 1. The dysfunction of ...
In a study published in Nature Methods, a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous ...
In a different type of signaling event, the scientists fused the binding proteins to a newly designed nanopore, a protein creating a channel allowing ion flow. The fused unit was constructed in such a ...
A pA-Tn5 probe (multicoloured) binds an antibody (white), which binds a transcription factor binding domain (green) on DNA (blue) within 2 nucleosomes. The binding of proteins to DNA is crucial for ...
In a study published in Nature Methods, a research group led by Prof. YE Mingliang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences (CAS), collaborating with Prof. LUO ...
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