Researchers find rare genetic mutation doesn't always result in blood cancer

Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in ...

Scientists uncover a genetic 'shield' that lowers the risk of colorectal cancer

A team of scientists from the Barbara Ann Karmanos Cancer Institute, Wayne State University and institutions across the U.S.
Nature

These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs

Biology has clever ways to mask the effects of potentially harmful gene mutations. Scientists are investigating how this ...

Scientists Uncover a Rare Genetic Key to Longevity That Could Delay Chronic Disease by 13 Years

Researchers recently identified 12 genetic variants linked to longer lives, potentially paving the way for anti-aging ...
Medical Xpress

Mitochondrial DNA mutation accumulation may not be a determining factor in aging

The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell ...
Labroots

A Mitochondrial DNA Mutation that Alters Immunity

Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little organelles are very special, because they also carry their own tiny little ...
Medical Xpress

Single DNA mutation disrupts key tumor-suppressing pathways, elevating blood cancer risk

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer ...

CRISPR safety check evaluates intended and unintended mutations

A team of researchers led by Professor Akitsu Hotta (Department of Clinical Application) developed a comprehensive framework ...
Labroots

A 'Junk DNA' Mutation That Prevents a Disease

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...
Nature

Beyond colonoscopy, faecal DNA mutation screening provides a potential and viable path to early colorectal cancer detection

Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide, with early detection critical for improving clinical outcomes. In Denmark’s CRC screening program, ...
Phys.org

Scientists use gene editing to correct harmful mitochondrial mutations in human cells

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...