The mammalian intestine is renewed every 4–5 days. Intestinal stem cells (ISCs), which reside in the crypts, continuously proliferate to fuel the high turnover of the intestinal epithelium 1. ISCs ...

A new study suggests that stem cells are able to integrate cues from their surroundings and coordinate their behavior across tissue through networks of vasculature in their close vicinity. To act as a ...

In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut regeneration and long-term stability. Their findings may have ...

During amphibian metamorphosis, a postembryonic developmental process, the thyroid hormone T3 induces multiple responses across organs and tissues, including intestinal remodeling. Indeed, the ...

Researchers at the University of Gothenburg have been studying the mucus involved in defending the intestines and airways against infection for more than 30 years. To date, their work has focused very ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures and villi in the intestine using a contact protein printing technique. This model ...

Your gut is a wondrous place. A special layer of cells that coats the insides of your small and large intestines takes in nutrients and water from what you ate while keeping anything bad out of your ...

Intestinal epithelial cells line the inner wall of the gut, creating a barrier against dangerous bacteria like enteropathogenic E. coli that seek to attach to and destroy this barrier. Such pathogens ...

The epithelial lining of our intestine is organized in a crypt-villi architecture and serves many essential functions including maintenance of barrier, digestion and nutrient absorption. Due to the ...

Chemical and Biological Engineering PhD student Max Yavitt is the lead author on a new paper in Science Advancesthat focuses on intestinal tissue research. The work could allow researchers to control ...

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task. The intestine’s resident ...

Stem cells are a hot topic for creating medical treatments. However, scientists still do not fully understand how they choose to divide or differentiate to renew organs. Researchers have now found a ...