Genome rearrangement algorithms constitute a fundamental pillar in comparative genomics, enabling the quantitative assessment of the evolutionary steps that differentiate species. These algorithms ...
The plastid genome (plastome) represents an indispensable molecular resource for studying plant phylogeny and evolution. Although plastome size is much smaller than that of nuclear genomes, accurately ...
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Replacing large mouse gene regions with human DNA
Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.
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