Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...
Clathrin triskelions, comprised of three clathrin heavy chains (CHC) and three tightly associated light chains (CLC), assemble into a polygonal lattice, which helps deform the overlying plasma ...
When human erythroleukemic cells are induced to differentiate, they produce globin and redistribute glycophorin and spectrin to one pole of the cell. This process was accompanied by an alteration in ...
Clathrin-mediated endocytosis (CME) is an essential cellular process that mediates the internalisation of diverse plasma membrane components and extracellular cargo. This mechanism relies on the ...
In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles. Cells employ several pathways for ...
This study is reported by Hualan Chen’s group from the State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences.
The paper S. Kaur et al., “An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis,” eLife, 3:e00829, 2014. For decades, scientists observed clathrin-mediated ...
The distribution of a number of membrane proteins on plasmalemmal microdomains (microvilli, coated pits) and in endosomes and lysosomes of the proximal tubule epithelial cell was determined in normal ...
Cells have a clever way called clathrin-mediated endocytosis to transport cargos like growth factors across the cell membrane and into the cell. Researchers used a sophisticated fluorescence ...
New Haven, Conn. -- Using state of the art imaging technology a team from Yale School of Medicine has glimpsed one of the cell's most important 'nano-machines' in action. The work, performed in ...
The outside of a cancer cell is bombarded by signals. They come from the immune system, supporting tissues and other structures. But how do those signals impact cancer? A new study provides a ...
In the late 1970s, scientists were divided on how viruses enter and infect host cells. Some investigators thought viruses were directly penetrating the cell membrane into the cytoplasm, while others ...
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