The question of how genetically identical cells organize themselves into the intricate, spatially ordered structures that form tissues, organs and, ultimately, entire organisms lies at the heart of ...

The spatial organization of cells within tissues is a fundamental determinant of their physiological functions. Each tissue exhibits a unique architectural layout composed of a three-dimensional ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...

One of the most fundamental processes in all of biology is the spontaneous organization of cells into clusters that divide and eventually turn into shapes – be they organs, wings, or limbs. Scientists ...

The immune system is a complex response of various cells that detect and elicit mechanisms to eliminate disease. This orchestrated response in healthy individuals overcomes infections and foreign ...

Using an innovative combination of biochemical experiments and ultra-high-resolution microscopy, a research team at Kiel ...

Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic ...

Aging affects every organ in the body, yet we still know little about how the ovary changes over time. In a new study published in Nature Aging, Yale researchers created one of the most detailed maps ...

Spatial proteomics enables scientists to investigate protein organization at the subcellular, cellular, and tissue levels, including in pathological contexts. Using technologies that help researchers ...

Lucy Shapiro received this year’s Lasker Special Achievement Award for her discovery of how bacteria use genetic circuits to encode three-dimensional cellular life. “I was quite shocked, truly,” said ...