A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...

Deep brain stimulation – implants in the brain that act as a kind of 'pacemaker' – has led to clinical improvements in half of the participants with treatment-resistant severe depression in an 'open ...

Deep brain stimulation—implants in the brain that act as a kind of "pacemaker"—has led to clinical improvements in half of the participants with treatment-resistant severe depression in an open-label ...

Researchers have found that even after recovery, individuals who previously experienced depression may retain a heightened sensitivity to negative cues and face challenges in regulating responses to ...

Exercise can powerfully influence the brain, but what if the same biological signals could be activated without physical movement?

Brain implants that deliver electric pulses can ease depression in people who aren't responding to psychiatric drugs, a new study says. Half of a small group of people who received brain implants ...

Young adults with depression exhibit unusual cellular energy patterns in both their brains and blood, characterized by cells ...

Understanding what depression is – and what it is not – is often the first step toward relief.

Live Science spoke with the scientists behind an upcoming clinical trial testing an immune therapy for depression.

For the first time, Americans with depression will soon be able to use a prescription brain-stimulation device at home. The approval comes from the U.S. Food and Drug Administration and marks a major ...