Lewy body diseases -- Parkinson's disease and dementia with Lewy bodies -- should be defined as neuronal alpha-synuclein disease, not as clinical syndromes, a new position paper proposed. "Parkinson's ...

Lewy body dementia is a progressive neurodegenerative disease that shares traits with both Parkinson’s and Alzheimer’s diseases but can be more difficult to diagnose. Symptoms can include ...

— Treatment of Parkinson's and Lewy body patient brain tissue with WTX-607 demonstrated highly specific binding to aggregates within neurons in patients' brain tissue and potent inhibition of ...

Lewy body dementia is a progressive neurodegenerative disorder brought on by an excess of the protein alpha-synuclein in the brain. These deposits, known as Lewy bodies, can inhibit the production of ...

Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for Parkinson's disease from cell-to-cell in the brain. In a paper published last ...

Nilotinib (Tasigna) — a drug for myeloid leukemia — improved biomarkers and cognitive outcomes in study participants with dementia with Lewy bodies, a new study finds. The phase II trial was small, ...

SynuSight Biotech has licensed 18 F-FD4 to XingImaging and to ABLi Therapeutics to evaluate alpha-synuclein clearance from the brain in response to risvodetinib treatment . SHANGH ...

Q: My husband was just diagnosed with Lewy Body Dementia. Can you help me understand this? A: I am sorry about this recent diagnosis. Lewy Body Dementia (LBD) is a complex and challenging brain ...

Researchers have been chasing the causes of Parkinson’s disease for more than a century, yet its hallmark feature — microscopic protein clumps called Lewy bodies — remains enigmatic: Patients with ...

While Alzheimer’s disease is the most common type of dementia, there’s another variation that is also relatively prevalent. Lewy body dementia (LBD) affects more than 1 million people in the US. It is ...

Johns Hopkins Medicine scientists have found that air pollution can trigger the formation of a unique strain of αSyn protein clumps in mice, resembling those seen in Lewy body dementia. Compared with ...