Acinar-to-ductal metaplasia (ADM) is a mechanism needed for regeneration after inflammation or injury ADM is a result of epigenetic silencing of markers of acinar cell identity, activation of drivers ...

Cisplatin and Etoposide Regimen Is Superior to Cyclophosphamide, Epirubicin, and Vincristine Regimen in Small-Cell Lung Cancer: Results From a Randomized Phase III Trial With 5 Years’ Follow-Up ...

Pembrolizumab in Patients With Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study Both somatic and germline analyses were performed ...

Organoids are three-dimensional miniature models of organs, grown in a dish. They have become a valuable tool for studying human development, organ regeneration, function, and disease progression.

Organoids are three-dimensional miniature models of organs, grown in a dish. They have become a valuable tool for studying human development, organ regeneration, function, and disease progression.

The increase in pancreatic cancer cases is closely tied to high insulin levels. Now, a new study reveals a direct link between high insulin levels, common among patients with obesity and Type 2 ...

Organoids are three-dimensional miniature models of organs, grown in a dish. They have become a valuable tool for studying human development, organ regeneration, function, and disease progression.

The patient is a 60-year-old man who presented with obstructive jaundice. In the course of evaluation he was found to have a mass in the head of the pancreas. He underwent laparotomy, which showed an ...

Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

The pancreas, located behind the stomach, manages the energy supply in our body. It does so by secreting proteins (enzymes) responsible for glucose – the body's main fuel – reaching other organs when ...