In sweeping attacks that started early Friday, Israel has struck at the regime in Tehran, targeting Iranian nuclear and military assets. The Israeli strikes have killed more than 70 people, including four top security chiefs, and damaged Iran’s main nuclear site at Natanz.

Fox News’ Alex Hogan and Mark Meredith report on the strikes between Israel and Iran, and reaction from the United States. Heritage Foundation senior fellow Brent Sadler joins ‘Fox News Live’ to analyze the future of Iran’s nuclear program.

Tehran said American bases in the Middle East could face reprisals if the U.S. helped repel Iranian attacks on Israel.

The United States is the main international backer of Israel, Iran's biggest regional foe. It is also a close ally of Sunni Gulf monarchies which for years pursued their own rivalry with the Islamic Republic, seeing it as their main regional threat.

Iran and Israel continued trading missiles and airstrikes on June 14, a day after Israel launched a sweeping air offensive against its old enemy.

Sirens sounded in Israel as Iran launched dozens of ballistic missiles in retaliation for Israel's strikes on its nuclear facilities.

The United States has pulled some diplomatic staff and military families out of the Middle East, citing unspecified regional security risks.

Israel’s leader and President Trump appeared to bet they can persevere, but other world leaders warned of unintended outcomes in a volatile region.