Here are three causes for concern for the Bills against the Patriots in Week 18: Let’s make one thing clear: the Bills are not very concerned with the outcome of the Week 18 game. But the obvious concern for losing stems from resting their key players.

See who's in and who's out for the Week 18 matchup between the Buffalo Bills and New England Patriots on January 5, 2025.

The Buffalo Bills (13-3) bring a three-game winning streak into a matchup against the New England Patriots (3-13) on Sunday, January 5, 2025 at Gillette Stadium. Buffalo is just 2.5-point favorite

Following their Week 17 victory over the Jets to clinch the AFC’s No. 2 seed, the Bills head into their regular-season finale against the Patriots with an opportunity to breathe before the playoffs begin. Without any stakes that impact their playoff path, Week 18 presents an opportunity.

Pregame analysis and predictions of the Buffalo Bills vs. New England Patriots NFL game to be played on January 5, 2025 on ESPN.

Josh Allen is set to make his 115th consecutive start for the Buffalo Bills in their regular-season finale despite the team clinching the No. 2 seed in the AFC playoffs. Head coach Sean McDermott supports Allen's decision to maintain his streak,