Iran and the United States will hold talks Friday in Rome, their fifth round of negotiations over Tehran’s rapidly advancing nuclear program. The talks follow previously negotiations in both Rome and in Muscat,

"We don't think it will lead to any outcome," the supreme leader warns, saying the US is making "outrageous" demands on uranium enrichment.

Iran’s Supreme Leader Ayatollah Ali Khamenei said he does not expect negotiations with the United States over Tehran’s nuclear program to “reach a conclusion” as Washington toughens its conditions for a deal.